Epigenetics · Science Writing · Scientific Illustration

Alice
Frolov

Science writer and scientific illustrator working at the boundary of epigenetics and chromatin biology — synthesising primary literature into structured, open-access publications and producing original scientific figures.

Epigenetics DNA Methylation Epigenetic Clocks Chromatin Biology Science Writing Scientific Illustration OSF · Open Access
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01 About
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I write and illustrate at the intersection of epigenetics, chromatin biology, and cellular aging — synthesising primary literature into structured, open-access publications hosted on OSF.

My work spans science writing and scientific illustration, with a focus on making complex molecular biology accessible without sacrificing rigour. I produce original figures for publications and visual essays covering epigenetic mechanisms, aging pathways, and chromatin-level regulation of gene expression.

Methodological focus: literature synthesis · computational annotation · figure design. All publications are openly accessible with permanent DOIs.

02 Publications & Works

All works are preprints hosted on OSF. Not peer-reviewed.

Research Notes
Molecular Mechanisms of Cellular Aging and Rejuvenation Strategies — Vol. I–III

Three-volume systematic review: hallmarks framework, regulatory pathways (mTOR, sirtuins, AMPK), and current rejuvenation interventions.

Alice Frolov · OSF · January 2026 · osf.io/dq8pz
Open Access
Emerging Biotechnologies in Human Enhancement: A Critical Assessment

Critical survey of biotechnologies at the frontier of human physiology — gene editing, neural interfaces, and substrate-level intervention — with analysis of technical feasibility and regulatory landscape.

Alice Frolov · OSF · January 2026 · osf.io/hybj5
Open Access
Literature Notes
Methodological assumptions in the Horvath pan-tissue methylation clock

Analytical notes on Horvath (2013) — training set composition, CpG site selection criteria, and the biological interpretation of cross-tissue age convergence.

Alice Frolov · Reading notes · 2026
Annotation
Epigenetic alterations as primary hallmark: notes on López-Otín et al. 2023

Close reading of the revised 12-hallmark framework — with attention to the causal hierarchy placing epigenetic alterations upstream of downstream hallmarks.

Alice Frolov · Reading notes · 2026
Annotation
03 Scientific Illustrations

Original figures produced to accompany publications and visual essays on epigenetics and aging biology.

Molecular Pathway Diagrams

mTOR, sirtuin networks, NAD⁺ metabolism — original figures for publications

Epigenetic Mechanisms

CpG methylation, histone modification, chromatin remodelling schematics

Hallmarks Framework

López-Otín 12-hallmark visualisations and inter-hallmark relationship diagrams

Cell Biology Figures

Cellular senescence, SASP signalling, epigenetic drift mechanisms

04 Focus Areas
DNA Methylation

CpG island dynamics, DNMT regulation, methylation clocks as biomarkers of biological age

Epigenetic Clocks

Horvath, Hannum, GrimAge — algorithmic biological age estimation and its biological basis

Chromatin Remodelling

Histone modifications, nucleosome positioning, and heterochromatin loss in aging

Epigenetic Reprogramming

Partial Yamanaka reprogramming, epigenetic age reversal, in vivo reprogramming strategies

Cellular Senescence

Epigenetic basis of senescence entry, SASP regulation, senolytic clearance

Hallmarks of Aging

López-Otín 2023 framework — epigenetic alterations as primary hallmark and causal driver

05 Curriculum Vitae
Curriculum Vitae
Alice Frolov — Academic CV
PDF · March 2026
Download PDF →
06 Contact

Open to correspondence on epigenetics, chromatin biology, science writing, and scientific illustration.

For collaboration, peer feedback on preprints, or general enquiries — write directly.

contact.alicefrolov@gmail.com