Alice Frolov

Where I Am

Buenos Aires, Argentina. Still relatively new to the city — finding my rhythm, learning the streets, and getting comfortable studying in Spanish full-time.

Studying

Completing secondary education through adult school (2026–2028) — a requirement for UBA admission. Simultaneously taking Spanish language courses at UBA itself, which is both practical and a bit meta.

The core of my self-directed study right now is epigenetic clocks and Yamanaka factor reprogramming — the idea that you can partially reset a cell's biological age by expressing four specific transcription factors. It's one of the most exciting areas in longevity research and I'm working through the primary literature systematically.

Writing

• Vol. IV of the Molecular Mechanisms of Cellular Aging series — on therapeutic interventions
• A longer essay on epigenetic reprogramming for Substack
• Experimenting with shorter-form notes on Medium for broader audiences

Reading

• Horvath & Raj (2018) — DNA methylation-based biomarkers and the epigenetic clock
• Sinclair, Lifespan — revisiting with more context than I had the first time
• Papers from the Conboy lab on heterochronic parabiosis

Full reading log on the Reading page →

Building

• This website — slowly making it a real home on the internet
• A Zenodo workflow for publishing study notes with proper DOIs
• Daily habits: physiotherapy routine, consistent sleep, deliberate Spanish immersion